Both are colour ink-tank printers with automatic duplex printing, USB, Wi-Fi, Wi-Fi Direct, AirPrint, and Mopria. Each has a 100-sheet rear feed, so these shared features do not separate them.
The L4360 prints, scans, copies, and prints borderless; the GX5050 is listed as print-only and explicitly lacks borderless printing. In turn, the GX5050 has ISO speeds of 24 ipm black and 15.5 ipm colour versus 15 and 8. It also has Ethernet, 350 rather than 100 sheets of input, and 100 rather than 30 of output. Replacement-black-ink yield favours the L4360, while replacement-colour-ink yield favours the GX5050; these are separate figures.
The L4360 may suit users who need scanning, copying, or borderless printing alongside printing. The GX5050 may suit print-only needs with faster ISO rates, wired networking, and more paper capacity. Its maximum-paper-size listing includes Legal, while the L4360 lists A4 / Letter.